Antimicrobial Drugs – Fleming and Penicillin [PPT]


Content Summary Overview

Antibiotic: Chemical produced by a microorganism that kills or inhibits the growth of another microorganism
Antimicrobial agent: Chemical that kills or inhibits the growth of microorganisms.

Chemotherapy: The use of drugs to treat a disease. Selective toxicity: A drug that kills harmful microbes without damaging the host

Semisynthetic Penicillins

Penicilinase-resistant penicillins
Carbapenems: very broad spectrum
Monobactam: Gram negative
Extended-spectrum penicillins
Penicillins + lactamase inhibitors

The Future of Chemotherapeutic Agents

Antimicrobial peptides
Broad spectrum antibiotics from plants and animals
Squalamine (sharks)
Protegrin (pigs)
Magainin (frogs)
Antisense agents
Complementary DNA or peptide nucleic acids that binds to a pathogen’s virulence gene(s) and prevents transcription


File Category: Health
File Added: Friday, April 8th, 2011
File Source: microvet.arizona.edu
File Size: 1.25 MB
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